Endocrine Abstracts

Background: Cardiovascular stratification and prevention in type 2 diabetic patients represent a major public health preoccupation in order to reduce their mortality. Several methods of detecting atherosclerosis have been developed such as biomarkers. The aim of this study was to evaluate the association between B-type natriuretic peptide (BNP) and cardiovascular risk (CVR) in type 2 diabetic patients.Methods: We conducted a cross-sectional study in 71 t...

Introduction: Metformin is a cornerstone in the treatment of type 2 diabetes, but in recent years several studies have shown that metformin use is associated with a 4-24% decrease in vitamin B12 levels. It is estimated that this problem occurs in approximately 10-30% of patients using metformin and may contribute to distal symmetrical polyneuropathy (DSPN), a very common and clinically relevant diabetic complication.Objective: To study vitamin B12 concen...

Introduction: Several studies have evaluated the prevalence and impact of metformin induced vitamin B12 deficiency in type 2 diabetes patients. On the other hand, low vit B12 was associated with adverse lipid profile.Aim: To evaluate the relationship between vitamin B12 deficiency and the lipid profile in patients with neuropathy.Patients and methods: A cross-sectional study included 123 type 2 diabetic patients treated with metfor...

Introduction: Diabetic retinopathy (DR) is a serious microvascular complication of type 2 diabetes and the leading cause of blindness worldwide. Several studies have reported the association between metformine-induced vitamin B12 deficiency in type 2 diabetic patients. However, the association between vitamin B12 and DR has only been investigated in few studies.Materials and methods: A cross-sectional study was carried out on 123 type 2 diabetic patients...